In part 1 of this post, I discussed the very basics of neuronal modelling. We discussed the fundamental equations that explain how ion channels create current and how current changes the membrane potential. With that knowledge, we created a simple one-compartment model that had capacitance, and a leak ion channel. But we didn’t have any action potentials. In order to model action potentials, we need to insert some mechanism to generate them. There are several ways of doing this, but the most common is the Hodgkin and Huxley (HH) model. I’m going to dive straight in to understanding the HH model, and as usual, I’m going to start from the ground floor.
